Central Serous Chorioretinopathy (CSC)

Central serous chorioretinopathy (CSC), is an eye disease which causes visual impairment, often temporary, usually in one eye, mostly affecting males in the age group 20 to 50 but which may also affect women.

When the disorder is active, it is characterized by leakage of fluid under the retina that has a propensity to accumulate under the central macula. This results in blurred or distorted vision (metamorphopsia). A blurred or gray spot in the central visual field is common when the retina is detached. Reduced visual acuity may persist after the fluid has disappeared.

The diagnosis usually starts with a dilated examination of the retina, followed with confirmation by optical coherence tomography and fluorescein angiography.

CSC is a fluid detachment of macula layers from their supporting tissue. This allows choroidal fluid to leak into the subretinal space. The build-up of fluid seems to occur because of small breaks in the retinal pigment epithelium.

CSC is sometimes called idiopathic CSC which means that its cause is unknown. Nevertheless, stress appears to play an important role. CSC has also been associated with cortisol and corticosteroids.